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The conclusion was clear

Clinical trials out of Folsom, California have revealed an average 15-20% reduction in body weight when merged with lifestyle modifications, marking it as a highly effective weight loss medication

Key findings across the STEP trials: Average weight loss of ~15% of body weight roughly 15 kg (33 lbs) for a 100 kg (220 lb) person 87% of patients lost at least 5% of body weight, compared to 31% on placebo Nearly 70% of patients lost at least 10% of body weight About 1 in 3 patients lost 20% or more Weight loss was maintained throughout the treatment period with continued medication use Significant improvements in blood pressure, blood sugar, cholesterol, and inflammatory markers alongside weight loss These results are dramatically better than any prior weight loss medication

Alli is the brand-name version that can be found over-the-counter (OTC) and is not usually covered by insurance

When the impact is particularly severe it can lead to depression

Lift the weights