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The pigmentation may be the result of an increase in the number of melanocytes in the basal cell layer of the oral epithelium, or of increased melanin biosynthesis by the melanocytes

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Dhaunsi GS., et al

This pairing allows researchers to study whether dual-pathway targeting (amylin + GLP-1) produces superior outcomes compared to single-agent protocols, with cagrilintide addressing gastric motility while semaglutide modulates incretin signalling independently

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Biochemical determination showed a decrease in the levels of blood lactic acid and blood urea nitrogen (BUN), increased hepatic glycogen storage, reduced malondialdehyde (MDA) levels, and enhanced superoxide dismutase (SOD) and glutathione peroxidase levels