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However, in this study we did not observe any changes in the expression of EMT markers or migratory and invasive capacity of patient-matched primary and metastatic cells treated with EPAC inhibitor that consistently downregulated TXNIP

This name combines Cagri from cagrilintide and Sema from semaglutide, representing the dual-peptide approach

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HFD-fed Ssu72 aKO mice displayed significantly downregulated mRNA expression of key regulators of lipid accumulation, including Pparg , Cebpa , Acaca , Fasn , Cd36 , and Dgat1 , compared to WT mice (Fig

& Almqvist, C