68 Diabetic cerebral microangiopathy has multiple complex changes in images (cerebral atrophy, subcortical microinfarcts, cerebral white matter hyperintensity, lacunar infarction, perivascular space, and cerebral microhemorrhage), 69 with diffuse adverse effects
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Longitudinal studies in spontaneously hypertensive stroke-prone have demonstrated that gut dysbiosis precedes the onset of hypertension and is marked by shifts in bacterial community structure and altered tryptophan-kynurenine metabolism, implicating microbial pathways in the early development of hypertension and related neurovascular complications (Shi et al., 2022)
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Turpin W, Lee SH, Raygoza Garay JA, Madsen KL, Meddings JB, Bedrani L, Power N, Espin-Garcia O, Xu W, Smith MI, Griffiths AM, Moayyedi P, Turner D, Seidman EG, Steinhart AH, Marshall JK, Jacobson K, Mack D, Huynh H, Bernstein CN, Paterson AD, Croitoru K, Crohns and Colitis Canada Genetic Environmental Microbial Project Research Consortium
doi: 10.1016/S0076-6879(94)33026-3 20 MartnezMCAndriantsitohainaR