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J Biol Chem (2018) 293:550921
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The conventional titration pattern ramps up to a 4 mg, 8 mg, or 12 mg maintenance dose after the 12-week introduction
Furthermore, 1919 PSPH V116I GBM cells exhibited enhanced synthesis of NADP compared to 1919 GFP control cells, reflected by the higher levels of m + 10 NADP isotopologues, while no changes in cellular NADP levels were observed
Heart: freshly isolated hearts were washed 3 times with ice cold PBS to remove excess blood before being placed in Buffer A containing 180 mM KCl, 4 mM EDTA, and 10 mg of BSA