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LY3298176, a novel dual GIP and GLP1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept

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Suganuma Y, Shimizu T, Sato T, Morii T, Fujita H, Harada Sassa M et al (2020) Magnitude of slowing gastric emptying by glucagon-like peptide-1 receptor agonists determines the amelioration of postprandial glucose excursion in Japanese patients with type 2 diabetes

It has been demonstrated that PP is released by other gut hormones such as ghrelin, motilin and secretin, but somatostatin was shown to inhibit its release

Clin Pharmacokinet 65 , 10871099 (2026)

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