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'GLP-1 receptor agonists: multi-agonists and the future.' Journal of Clinical Investigation

Overall, these data do tentatively support the possibility that biased GLP1 agonists might be associated with a lower rate of nausea than standard agents, although GLP1 agonists displaying a more extreme level of bias (e.g., TTP273) might be less effective for weight loss

10.1016/j.intimp.2015.11.023 70 LiM.LiY.XiangL

Many research protocols default to SubQ for simplicity and reserve IM for specific site-based research questions