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The absorption of levothyroxine and other thyroid hormone preparations may be affected by concurrent use of Semaglutide / Cyanocobalamin Injection

Other Drugs : Vitamin B12 can interact with other drugs, such as folic acid, affecting their efficacy or increasing the risk of side effects

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On the pills I separated the capsule and mixed contents in a Churu and the cat loved eating it

Not because they're unsafe, but because the weight loss magnitude in controlled trials wasn't commercially viable compared to GLP-1 agonists or other obesity drugs