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Of significance and supporting a potential anti-cancer action of metformin is that LKB1 is a tumor suppressor and that mutations in LKB1 are observed in numerous cancers that result in the reduction of the inhibitory effect of the LKB1/AMPK pathway on the pro-proliferative signaling via mTOR (125, 126)

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Its magnetic field extends so far into space that, if it glowed in visible light, Jupiter would appear to be twice the size of the full moon in our night sky, the New Yorker explains