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Some patients appreciate that thigh injections feel less noticeable during the day compared to abdominal sites

doi:10.1007/s10295-015-1707-5 Watanabe F, Hashizume E, Chan GP, Kamimura A (2014) Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women

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As always, this should be guided by a clinician familiar with functional and preventive strategies

Functional indicators Reduced appetite suppression: If the same dose that previously suppressed your appetite is suddenly less effective, potency loss is possible

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