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Free radicals aggressively attack lipids in the cell membranes, a process known as lipid peroxidation, which destroys the structural integrity of neurons and mitochondria alike

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For the NAM pretreatment groups, cells were incubated with 10 M Nicotinamide (NAM) for 18 h, followed by a 24 h treatment with either Rotenone (Rot

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In practical terms, this often pushes people back toward safer, non-pharmacologic options: topical self-tanners (dihydroxyacetone), controlled UV exposure with medical-grade phototherapy when indicated, or simply accepting natural skin tone and focusing on photoprotection