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Int J Mol Sci 23(1):14

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A gene expression signature associated with K-Ras addiction reveals regulators of EMT and tumor cell survival

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These include the precise role of SL hydrolysis in signal transduction, the identity of the SL degradation product retained by D14/HTL during complex formation with MAX2/D3 46,47 , and the mechanism by which receptorF-box association leads to substrate recognition and ubiquitination 48,49