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Temporal definition of haematopoietic stem cell niches in a large animal model of in utero stem cell transplantation

Epicutaneous (EC) immunization with type II collagen (COLL II) induces CD4(+) CD8(+) T suppressor cells that protect from collagen-induced arthritis (CIA)

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Proteins assessed included components of the Erk1/2 and Akt pathways, markers of oxidative stress, insulin-like growth factor-1 (IGF-1), apoptotic regulators (Bax and Bcl-2), and autophagy-associated proteins