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It acts as a selective antagonist of the sigma-1 receptor, a protein involved in various cellular processes, including neurotransmission and cell survival

In some embodiments, the otic formulations or compositions disclosed herein also contain preservatives, cosolvents, suspending agents, viscosity enhancing agents, ionic-strength and osmolality adjustors and other excipients in addition to buffering agents

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Additionally, it should be high in protein but low in fats, carbohydrates, and calories

[PubMed: 19168552] 473

And as more consumers educate themselves about what goes into their supplements, the demand for clean, synergistic, and purpose-driven formulations has only increased