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Thus, even if a product candidate is approved, sales of the product will depend, in part, on the extent to which third-party payors, including government health programs in the United States such as Medicare and Medicaid, commercial health insurers and managed care organizations, provide coverage, and establish adequate reimbursement levels for, the product

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In particular, we observed previously unreported, robust suppression of p70S6K, as well as suppression of p-4E-BP1 and p-S6 (Fig

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