Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein
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Nakatani Y, Maeda M, Matsumura M, Shimizu R, Banba N, Aso Y, Yasu T, Harasawa H
These incretin effects explain the initially surprising weight loss observed in the treatment groups of the cardiovascular trials, with subjects taking GLP-1/GIP agonists losing from 3% to 12% of their body weight
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