(History + Background) IGF-1 DES , or Insulin-like Growth Factor 1 DES(1-3) , is a modified version of IGF-1 a powerful anabolic growth factor that plays a critical role in: Muscle growth Tissue repair Recovery Cellular regeneration It is essentially a truncated form of native IGF-1: 13 amino acids shorter than full-length IGF-1 Lacks the first three N-terminal amino acids (hence the name DES(1-3) ) This structural modification gives IGF-1 DES two unique properties: Greatly increased receptor binding affinity 10x more potent locally vs
References Murakami T, Inagaki N, Kondoh H
More extensive clinical trials are needed to shed more light on the effectiveness of retatrutide for T2D, and whether it may be limited due to the activation of the GCG receptors, which may exert anti-insulin effects
Extended Description and Image Alt Text Extended Description Eight images of the giant planet Jupiter spanning approximately 90 days between December 2023 and March 2024
Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report
Sattler FR, Castaneda-Sceppa C, Binder EF, Schroeder ET, Wang Y, Bhasin S, Kawakubo M, Stewart Y, Yarasheski KE, Ulloor J, Colletti P, Roubenoff R, Azen SP