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Variants in STAT4 Associated With Cure of Chronic Hbv Infection in HBeAg-Positive Patients Treated With Pegylated Interferon-Alpha
doi: 10.1177/1756283X12459294 71 Hernandez-MontelongoJ.NicastroG
NF-B not only induces canonical pro-inflammatory cytokines (TNF-, IL-6, pro-IL-1) but simultaneously up-regulates facilitative glucose transporter, metabolically locking macrophages, DCs and activated T cells into a glycolytic, NO-rich phenotype that fuels chronic mucosal inflammation (11, 110112)
Less information is available about the three outlying minor GST classes including lambda GSTs (GSTL), dehydroascorbate reductases (DHARs), and tetrachlorohydroquinone dehalogenase (Dixon et al., 2002, 2009)