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However, disruption of this crosstalk in advanced disease may contribute to the progression toward metabolic failure (64)

MR helps mitigate confounding biases by leveraging the random allocation of genetic variants at conception and exclude reverse causation, as genetic determinants precede disease onset [26]

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It contains growth factors that stimulate tissue repair

51, 52 It activates NADPH oxidase and, subsequently, generates superoxide that leads to hypertrophy of the renal tubular cells

A complete medication review with your prescriber can identify potential interactions