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Institute for Health Metrics and Evaluation (IHME)

This means when you stop the medication and resume normal eating, you burn fewer calories at rest than before making weight regain even easier

Recognition of this has spurred a number of innovative approaches that, despite their preclinical promise, have yielded disappointing efforts at translation into a meaningful clinical role

According to IQVIA, this creates an unusually short branded exclusivity window: generic manufacturers are positioned to flood the market with lower-cost alternatives, potentially extending GLP-1 treatment to a far broader patient population

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"To be clear, microdosing of GLP-1 medications is not included in any official guidelines," says Dr