Improved Insulin Sensitivity: Insulin resistance is a common risk factor for many chronic diseases, including type 2 diabetes and metabolic syndrome
This allows you to eat less because your brain tells you your stomach is full, even after a smaller meal
However, they should be part of a balanced approach that includes nutrition, exercise, and adequate recovery
Blitz: Compounding medications like semaglutide and tirzepatide are only legally permitted under narrow circumstancesspecifically, during an FDA-declared shortage or when a patient requires a true, documented clinical difference, such as an allergy to an ingredient in the branded product
References include Jastreboff et al., New England Journal of Medicine , 2022 (SURMOUNT-1, tirzepatide for obesity), the FDA Zepbound prescribing information, the FDA Drug Shortages list (accessed Q1 2026), Patel et al., Annals of Pharmacotherapy , 2024 (compounded GLP-1 dosing errors), and the U.S
Managing Potential Side Effects: Your provider can offer guidance on common side effects such as nausea, vomiting, or changes in appetite