Current evidence suggests that these medications may provide cardiovascular benefits rather than harm for most patients
In OASIS 4, adults on the 25mg dose lost an average of 16.6% of their body weight over 64 weeks, with around 3 in 10 losing 20% or more
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These findings suggest that potential changes in thyroid hormone exposure after GLP-1RA initiation, possibly related to weight loss or altered absorption, may have important cardiovascular implications and warrant closer monitoring and further investigation
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Some people may take tirzepatide while using blood pressure medication, but this should be supervised by a healthcare provider