Catabolism of the murine IgG1 molecule: evidence that both CH2-CH3 domain interfaces are required for persistence of IgG1 in the circulation of mice
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Notably, we recently conducted LNP-mediated knock-in of the GFP gene at the Alb locus, with GFP expression predominantly observed in hepatocytes, further confirming that hepatocytes are primary target for LNP-mediated gene delivery and genome editing 13
Tissue healing, angiogenesis promotion, anti-inflammatory activity, gut protection, neuroprotection the accumulating animal literature continues to be both compelling and mechanistically coherent
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