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Although the beneficial role of liraglutide in osteoarthritis has long been acknowledged, it was not until recently that a study hypothesized this GLP-1RA mediated macrophage transition to an M2 anti-inflammatory phenotype, inhibiting pro-inflammatory cytokine release in a dose-dependent manner (Meurot et al., 2022)

Role of enteroendocrine L-cells in arginine vasopressin-mediated inhibition of colonic anion secretion

Ferroptosis and necroptosis thus form a self-amplifying, reciprocal loop mediated by ROS, RIPK3, and lipid peroxidation in ocular diseases, with RIPK3 serving as the molecular intersection (146)

[22] Suzuki, H