This activity may involve forming insoluble metal complexes or creating steric hindrance that inhibits interactions between metal ions and lipid intermediates
Furthermore, some people may experience a reddish colour of urine: this is a natural phenomenon as vitamin B12 contains cobalt
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With the exception of erlotinib, drugs known to be substrate of efflux transporter such as digoxin, loperamide, fluoro-A85380, verapamil and vinblastine are likely to be also ABC transporter substrates in the iPSC-hBBB model