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Vitrified complexes were imaged by cryo-EM yielding 2D class averages with well resolved secondary structure that were reconstructed into 3D consensus density maps with global resolutions of 2 monash.edu)

2D classification and selection were initially performed to ensure only highly resolved particles were further analysed

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In late 2026, Eli Lilly is expected to submit a New Drug Application (NDA) to the FDA once full Phase 3 data is compiled and analyzed