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Description

A 3D microfluidic BBB model is based on iPSCs from patients with AD mimicked vascular damage as an increased BBB permeability, a reduction in TJs and AJs, and an increased expression of the matrix-metalloproteinase-2 (MMP2) (Shin et al., 2019)

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Additionally, its manufacturing process incorporates various mechanisms to ensure maximum consumer safety

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10.1038/sj.jcbfm.9600525 J

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A.BaroneM

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