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Notably, these anti-fibrotic effects were amplified when EA was combined with metformin, highlighting the potential of EA as a synergistic component in integrative therapeutic strategies for MASLD (73)

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On the other hand, the overexpression of G6PD in vascular endothelial cells decreases the accumulation of ROSs in response to exogenous and endogenous stressors, improving bioavailable NO levels [54, 55]

The effect on cognitive function has also been examined in 36 individuals with Type 2 diabetes mellitus and mild cognitive impairment assessed by the Mini-Mental State Examination (MMSE) score

10.1080/15476286.2022.2066334 78 HuangF

Supplementing with NAC may provide additional support for kidney function, particularly in individuals with existing kidney conditions