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The aim of this chemical selection was to identify chemicals with highest relevance towards the perturbation of initiation and promotion of human adipogenesis, and for a candidate test method to ideally capture both, the commitment of precursor cells such as MSCs, to the (WAT) adipocyte lineage, and the subsequent promotion of intracellular lipid accumulation

The mechanism is plausible (direct delivery should theoretically accelerate results), but the evidence base is not comparable to what exists for topical application

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