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Some patients abandon therapy after reaching their target weight, while others are forced to pause or switch treatments due to supply shortages

For example, if you've been eating half your usual portions for two weeks, this explains why some values have changed since your last lab tests

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Notably, bi-allelic MC4R mutation carriers had long-term outcomes as poor as those with bi-allelic LEPR or POMC mutations, suggesting that biallelic mutations in LMP genes generally lead to more severe impairment of surgical efficacy compared to heterozygous mutations

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