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The side chains of the vitamin B12 forms were replaced with hydrogens, and the dimethylbenzimidazole ligand was replaced with an imidazole ring

An oral alternative that works as well as or better than existing options, and can be taken as easily as a daily vitamin, has the potential to meaningfully expand access

Lipids Health Dis 2013;12:98

This cost is because of the many years spent on research, clinical trials, and getting the right paperwork done

No loss of 5-methyl-THF was detected in spinach, broccoli, potatoes, strawberries, apples, oranges, and bananas frozen at 60 C after storage for 12 months 485

The journal article elaborates that anatomical barriers in the anterior eye and intracellular barriers within the lens contribute to the challenge of delivering glutathione to various lens regions