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The current study expands the application of pharmacologic MC4R stimulation by demonstrating that the MIA mouse model of autism is responsive to MT-II treatment, suggesting a promising approach for further clinical investigation regarding individuals with in utero exposure to infection

doi: 10.1074/jbc.M607955200 Summary Keywords ghrelin, ghrelin receptor (GHS-R1a), GPCR, structural biochemistry, orexigenic hormone Citation Shiimura Y, Kojima M and Sato T (2025) How the ghrelin receptor recognizes the acyl-modified orexigenic hormone

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