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Metabolism & aging (preclinical): NAD+-dependent sirtuin and PARP activity has been linked to DNA repair and metabolic regulation in animal models [11]

doi: 10.3389/fmolb.2022.1016090 Received 18 August 2022 Accepted 15 September 2022 Published 29 September 2022 Volume 9 - 2022 Edited by Ye Sun, Boston Children's Hospital, Harvard Medical School, United States Reviewed by Xudong Wang, Massachusetts General Hospital, Harvard Medical School, United States Xiujuan Shi, Tongji University, China Updates Copyright 2022 Ma, Yang, Zuo and Huang

The rank order of ligand-induced changes was consistent for matched TR-FRET and BRET approaches, with exendin-4-C16 showing reduced GLP-1R internalisation and lysosomal accumulation, but faster recycling

Intranasal BBB bypass is a validated human pharmacological route actively used for other biologics (e.g., intranasal oxytocin and insulin)

the different names just reflect different contexts (research code vs

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