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The variables mentioned above impact the proportion of vasodilation to vasoconstriction, the movement and growth of smooth muscle cells, the hindrance and encouragement of platelet adhesion and aggregation, and thrombogenesis and fibrinolysis (60)

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The diagnosis of Classic FMS fits the patient who has a significant sleep disorder, brain injury, depression, anxiety syndrome, and/or some other type of central nervous system dysfunction that leads to abnormal processing of sensory stimuli

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The systems affected can include the gastrointestinal tract, the respiratory system, the skeletal-muscular system, the immune system, the urinary system, and the nervous system