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Due to sequence similarities between GLP-1 and GIP, a chimera peptide of GLP-1 residues and certain C-terminal residues of GIP activates both the GLP-1 and GIP receptor (GIPR) [91]

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6 The recurrence rate in subsequent pregnancy is estimated at 69%, and some women have permanent hypothyroidism

Case 2 Case 2 was a 14-year-old Japanese boy, the second child of nonconsanguineous parents, who presented with severe ocular anomalies and neurodevelopmental delay