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Askelof, P., Axelsson, K., Eriksson, S

Rather than taking a massive dose of Vitamin D once a week, taking a moderate, highly bioavailable dose daily is generally more effective for maintaining stable blood levels

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This leads to the release and subsequent cytoplasmic translocation of p53, which in turn activates a transcription-independent pro-apoptotic pathway, facilitating the selective clearance of senescent cells (Kong et al., 2025