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This age-related decline has been a central focus of research interest

Information source: www.mdpi.com/journal/molecules

Alternatives in Class At a glance Brand Vyvanse (30-day supply) / $350 to $450 cash price Generic lisdexamfetamine (30-day supply) / $30 to $80 cash price (since August 2023) Generic mixed amphetamine salts XR / $15 to $50 per month Generic methylphenidate ER / $20 to $45 per month FDA-approved indications / ADHD (ages 6+) and binge eating disorder (adults) Duration of action / 12 to 13 hours in controlled trials DEA schedule / Schedule II controlled substance Prodrug conversion / Lisdexamfetamine is cleaved to d-amphetamine in red blood cells Patent expiration / August 2023 (first generics launched) Insurance tier / Tier 2 to 3 for generics

For the average healthy adult, 1000 mg is generally well-tolerated

PMID: 19875696

Significance was determined by two-way ANOVA with idks multiple comparison test ( c )