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PMID: 24428527

5.3.2 Second hit theory and complication warning The second hit theory underpins this clinical phenomenon (22)

Disposing of your medication Guide the used needle tip into the outer needle cap on a flat surface and once the needle is covered, carefully press the cap all the way on

BPC-157 and TB-500 Dosage Protocol BPC-157: 250500mcg daily, injected subcutaneously near the injury site TB-500: 22.5mg twice weekly (loading phase) for 46 weeks, then 2mg once weekly (maintenance phase) The combination is typically used for 612 weeks, depending on injury severity and healing progress

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Several preclinical studies have demonstrated that exposure to vitamin D can modulate the activity of the Klotho protein