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Konerman MA, Jones JC, Harrison SA (2018) Pharmacotherapy for NASH: current and emerging

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By week 68, 88.2% of those assigned to combination therapy remained on treatment

Receptor Binding and Downstream Signaling IGF-1 LR3 binds IGF1R with affinity similar to native IGF-1, preserving the receptor-level pharmacology while altering the pharmacokinetics