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Free Radic Biol Med 16:811820 Liu Y, Rosenthal RE, Starke-Reed P, Fiskum G (1993) Inhibition of postcardiac arrest brain protein oxidation by acetyl-l-carnitine

To cope with the elevated oxidative stress they generate, cancer cells enhance their antioxidant capacity, largely through sustained activation of the transcription factor NRF2 often driven by mutations in its negative regulator KEAP1

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This is in contrast to class I GRXs from poplar, where glutathionylation occurs at the same redox potential as disulfide formation 33

Phytomedicine, 9 (4), 325-337