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For example, controlled trials in diabetic polyneuropathy have employed 600 mg of ALA injected IV once daily (often given as an infusion over 30-60 minutes) for periods of 2-4 weeks, with significant efficacy observed in reducing neuropathic symptoms compared to placebo

After age 30, these are very common findings of a meniscal tear on MRI, which is of little consequence

Invading white blood cells secrete pro-inflammatory factors, which trigger reactive response of neural parenchymal cells, most notably reactive astrogliosis and microgliosis

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Basco L, Gillotin C, Gimenez F et al (1992) In vitro activity of the enantiomers of mefloquine, halofantrine and enpiroline against Plasmodium falciparum