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Six of the 8 patients (75%) experienced recurrence of their primary tumor within a median of 24 months, with 33% (n = 2) of recurrences occurring after 5 years of follow-up

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Spatial distribution is exemplified by DHHC5, which promotes apoptosis through RIPK1 modification, sustains autophagy via Beclin 1 palmitoylation, and regulates ferroptosis by maintaining TfR1 membrane localization

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For comparisons involving more than two groups, either an ordinary one-way ANOVA with Tukeys multiple comparisons test or a Friedman test with Dunns multiple comparisons test was applied

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