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This molecular signature correlated with dose-dependent increases in intracellular ROS and significant DNA damage in larval haemocytes
392,393 Iron accumulates in the parenchymal cells of various organs in HH patients, generating ROS through the Fenton reaction, resulting in ferroptosis and several serious chronic complications, including heart disease, diabetes, and cirrhosis
Specifically, the strongest inverse association between cruciferous vegetable intake and colon cancer risk is observed among younger individuals (particularly those under 55) with the GSTM1-null genotype, and the benefit appears more pronounced in smokers (62)
Meanwhile, proteomics elucidates the role of proteins in diseases by analyzing protein structures, providing a basis for drug design (Lee et al., 2011
