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For transparency: this article is educational and independent, and PlexusDx offers its own tirzepatide and semaglutide protocols

Market analysis shows the global obesity GLP-1 market was valued at about USD 8.21 billion in 2025 and is expected to reach roughly USD 66.57 billion by 2035, expanding at a CAGR of about 23% due to rising obesity rates and strong clinical effectiveness of GLP-1 drugs

44,45 In response to overnutrition, obesity and insulin resistance, beta-cells adapt by increasing their mass and/or number, both of which result in increased capacity of insulin secretion

Aim for at least 64 ounces (eight cups) of water daily, and increase this amount if you are experiencing GI side effects like diarrhea or vomiting

This mechanism reduces appetite and promotes satiety but also delays how foodand oral medicationsmove through your stomach and small intestine