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619 Likewise, the activity of glutamine synthetase is profoundly decreased in the brain tissue of AD patients due to protein oxidation

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AMG 133 results in full agonism of human GLP-1R (EC 50 = 24.4 pM) and activated cynomolgus monkey and mouse GLP-1R (EC 50 of 5.7 and 123 pM, respectively)

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