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Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide

Additionally, Principal Coordinates Analysis (PCoA) demonstrated major differences in the composition of the microbiota between these two groups, further emphasizing the modifications imposed by ATX on the intestinal microbiota of the MCAO rats (Fig

Together, these findings suggest that cellular resistance to cuproptosis also depends on a hierarchically organized copper-buffering system, in which mtGSH provides rapid, dynamic metal buffering, whereas metallothioneins confer sustained high-affinity sequestration to prevent mitochondrial copper overload

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Chapter 10 - Role of micronutrients zinc and selenium in inflammation and oxidative stress