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doi: 10.1074/jbc.275.5.3693

Saitoh M, Nishitoh H, Fujii M, Takeda K, Tobiume K, Sawada Y, Kawabata M, Miyazono, K and Ichijo H

for instance, DT-109 (Gly-Gly-Leu) markedly reduced atherosclerosis and vascular calcification in nonhuman primates, underscoring the translational potential of tripeptide-based therapeutics for cardiovascular diseases [181]

Tubular epithelial fibroblast transdifferentiation (TEMT) has been proposed as a viable therapeutic option to decrease RF since it stimulates the expression of several fibro-cytokines, which represent a critical mechanism in the development of RF (Li et al., 2004