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In an animal model, semaglutide demonstrated neuroprotective effects and improved cognitive function by inhibiting the release of inflammatory cytokines mediated by the NLRP3 inflammasome, a protein involved in regulating the innate immune system and inflammatory responses

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Introduction Gastrointestinal hormones, such as ghrelin and glucagon-like peptide-1 (GLP-1), control various functions within the digestive system while communicating with our central nervous system (CNS) as part of the gutbrain axis