New England Journal of Medicine, 373(23), 2247-2257
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In neurodegenerative diseases, disruptions in protein phosphorylation are often associated with the formation of abnormal protein aggregates, such as tau tangles in AD
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(2) Synaptic density in the hippocampus increased measurably in treated animals
In addition, advanced glycocalyx fixation techniques (such as HPF and FS), along with visualization methods like TEM, reveal variations in glycocalyx thickness across vascular beds, providing new insights into its structural heterogeneity [35]