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This hyper ECD motion was propagated to the receptor TMD, with motions within TMs 3 and 7, creating a wider TM pocket that also influences the positioning of the N-terminus of the Cagri peptide (Fig

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Glucagon-like peptide 1 (GLP-1) is a hormone that causes huge effects on the regulation of blood sugar by stimulating glucose-dependent insulin secretion

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While the ongoing SURPASS clinical trial aims to elucidate the mechanistic underpinnings of the drug and the best dosages for treating patients of varying BMIs, its benefits cannot be understated